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Chapter 15 Gene Regulation in Eukaryotes
Student: ___________________________________________________________________________
1. Which of the following would also work as an enhancer for the following bi-directional enhancer?
5 GTTC 3 3 CAAG 5
A. 5 GAAC 3 3 CTTG 5
B. 5 CTTG 3 3 GAAC 5
C. 5 CAAG 3 3 GTTC 5
D. More than one of the answers are correct
2. What structural motifs promote dimerization?
A. Zinc finger
B. Leucine zipper
C. Helix-turn-helix
D. Helix-loop-helix
3. Which of the following is a steroid receptor?
A. GRE
B. IRE
C. CRE
D. None of the answers are correct
4. Which is not an example of RNA processing regulation?
A. RNA concentration
B. RNA editing
C. Alternative splicing
D. eIF2a protein kinases
5. Based on the following mature mRNAs, what exons are constitutive?
I. 1-2-3-4-7-8-10 II. 2-4-5-6-7-9 III. 1-4-6-7-8 IV. 1-2-4-7-10
A. 1 and 2
B. 1 and 4
C. 2 and 7
D. 4 and 7
6. What is an example of RNA editing?
A. Changing a valine codon to a stop codon
B. Methylation of cytosine bases
C. Formation of RISC
D. Alternative splicing
7. Which of the following mRNAs would be found at the lowest concentration?
A. 5 GGAUGGCCGUUUGAAAAAAAAAAAAAAAAAAAAA 3
B. 5 GGAUGGCGACCUGAAUUUAAUUUAAUUUAAAAAA 3
C. 5 GGAUGGAAGUUUGAAUUUAAUUUAAAAAAAAAAA 3
D. 5 GGAUGGGGACUUGAAUUAAAAAAAAAAAAAAAAA 3
8. Where is the IRE located in the ferritin gene?
A. 5 end of DNA
B. 5 end of mRNA
C. 3 end of DNA
D. 3 end of mRNA
9. A mutation in which of the following would result in little or no expression of a gene regulated by a CRE?
A. G protein
B. Adenylyl cyclase
C. Protein kinase A
D. All of the answers are correct
10. What activates CREB?
A. Binding of cAMP
B. Phosphorylation
C. Dimerization
D. None of the answers are correct
11. What would be the result of a mutation in Hsp90?
A. Glucocorticoid receptor could not form a dimmer
B. The nuclear localization signal would no longer function
C. Expression of the regulated genes would become constitutive
D. The hormone would not be able to bind to the glucocorticoid receptor
12. Which mechanisms are used by miRNAs to regulate gene expression?
A. Targeted degradation of mRNAs
B. Targeted inhibition of mRNA translation
C. Both A and B
D. Neither A nor B
13. A person with a mutation in IRP that prevents it from binding iron. What effect will this have?
A. Ferritin will not be made, so iron intake must be maximized
B. There will be excess ferritin, so iron intake must be lowered
C. Transferrin will not be made, so iron intake must be maximized
D. There will be excess transferrin, so iron intake must be lowered
14. What mechanism of RNA regulation is responsible for the two different forms of apolipoprotein B?
A. Alternative splicing
B. RNA editing
C. RNA interference
D. Covalent modification of RNA
15. What basal transcription factor is most often affected by regulatory transcription factors?
A. TFIIB
B. TFIID
C. TFIIE
D. TFIIF
16. SR proteins are splicing factors rich in _____.
A. Arginine
B. Cysteine
C. Asparagine
D. Proline
17. Which of the following relationships is true?
A. The more stable an mRNA is, the higher its concentration
B. The more unstable an mRNA is, the lower its concentration
C. The more unstable an mRNA is, the higher its concentration
D. More than one of the answers are correct
18. eIF2a is phosphorylated in order to inhibit transcription. What is occurring at the molecular level?
A. Phosphorylated eIF2a binds to tRNAs, preventing them from attaching its amino acid
B. Phosphorylated eIF2a binds to eIF2B, inhibiting its activity
C. Phosphorylated eIF2a binds to the mRNA, blocking the Shine-Delgarno sequence and preventing translational initiation
D. All of the answers are correct
19. S1 nuclease will cleave which of the following?
A. Double-stranded DNA
B. Single-stranded DNA
C. A single-stranded probe hybridized to a particular gene
D. Chromosomal DNA in an open conformation
20. In which of the following scenarios would gene expression be the lowest?
A. The CpG island upstream of the gene is unmethylated
B. Injecting antisense RNA corresponding to the mRNA of the gene
C. Deletion of a sequence upstream of the gene known to be a silencer
D. Injecting double-stranded RNA corresponding to the mRNA of the gene
21. Transcription factors recognize which of the following?
A. Response elements
B. Control elements
C. Regulatory elements
D. All of the answers are correct
22. Which of the following is an example of a motif found in transcription factors?
A. Zinc finger
B. Leucine zipper
C. Helix-turn-helix
D. Helix-loop-helix
E. All of the answers are correct
23. Regulatory transcription factors may influence gene expression in which of the following ways?
A. Recruiting proteins to the promoter that enhance chromatin compaction
B. By effecting the ability of TFIID to bind to the core promoter
C. Influencing the ability of the RNA polymerase to form an initiation complex
D. All of the answers are correct
24. Regulatory transcription factors may be regulated by __________.
A. Covalent modifications
B. Protein-protein interactions
C. Use of effector molecules
D. All of the answers are correct
25. Which of the following is incorrect regarding the glucocorticoid hormomes?
A. They interact with receptors located in the plasma membrane of the cell
B. After interacting with the receptor, they release HSP90
C. The receptors form a homodimer that travels to the nucleus
D. The homodimer interacts with GRE, activating transcription
26. cAMP is known as a second messenger system since the pathway is first activated by a extracellular signaling molecule
True False
27. Which one of the following directly interacts with the DNA as a transcriptional regulator?
A. cAMP
B. G protein
C. Protein kinase A
D. CREB protein dimmer
E. None of the answers are correct
28. RNAi is used in eukaryotic cells only to defend against viruses and transposable elements.
True False
29. Histone acetyltransferases would be directly involved in which of the following?
A. Formation of open chromatin
B. Movement of the nucleosome
C. Acetylation of lysines
D. Termination of gene expression
30. CpG islands are associated with which of the following?
A. Nucleosome location
B. DNA methylation
C. Steroid hormone activity
D. cAMP pathway
31. Genomic imprinting is a result of ___________.
A. Nucleosome location
B. Histone activation
C. DNA methylation
D. Serine to leucine changes in the genetic code
32. The exons of a gene are always expressed in a functional protein.
True False
33. Guide RNA is used in which of the following processes?
A. DNA methylation
B. Alternative splicing
C. Chromatin condensation
D. RNA editing
E. None of the answers are correct
34. The stability of mRNA is due mostly to which of the following?
A. GC content of the message
B. Poly-A binding protein
C. Methylation
D. 5 capping
E. Alternative splicing
35. Explain why yeast genes with a single intron have essentially no alternative splicing.
A. Yeast genes never have alternative splicing.
B. Removal of a single intron leads to splicing of the poly-A tail which prevents further splicing.
C. Methylation of the single intron prevents further splicing.
D. Removal of a single intron only leads to one possible outcome for spliced mRNA.
E. None of the above.
36. Transcription factors are proteins that influence the ability of the RNA polymerase to transcribe a gene.
True False
37. Activator proteins bind to silencer sequences and repressor proteins bind to enhancer sequences.
True False
38. If a portion of a transcription factors domain is the same in a variety of organisms, it is called a motif.
True False
39. A heterodimer occurs when two identical transcription factors interact on a sequence of DNA.
True False
40. A repressor protein would enhance the ability of TFIID to bind to the TATA box of the promoter.
True False
41. Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.
True False
42. Receptors for steroid hormones are usually found in the nucleus of the cell.
True False
43. DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.
True False
44. Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.
True False
45. DNA methylation activates gene expression.
True False
46. Housekeeping genes are unmethylated and active in most cells.
True False
Chapter 15 Gene Regulation in Eukaryotes Key
1. Which of the following would also work as an enhancer for the following bi-directional enhancer?
5 GTTC 3 3 CAAG 5
A. 5 GAAC 3 3 CTTG 5
B. 5 CTTG 3 3 GAAC 5
C. 5 CAAG 3 3 GTTC 5
D. More than one of the answers are correct
Blooms Level: 5. Evaluate
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
2. What structural motifs promote dimerization?
A. Zinc finger
B. Leucine zipper
C. Helix-turn-helix
D. Helix-loop-helix
Blooms Level: 3. Apply
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
3. Which of the following is a steroid receptor?
A. GRE
B. IRE
C. CRE
D. None of the answers are correct
Blooms Level: 2. Understand
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones.
Section: 15.01
Topic: Gene Regulation
4. Which is not an example of RNA processing regulation?
A. RNA concentration
B. RNA editing
C. Alternative splicing
D. eIF2a protein kinases
Blooms Level: 4. Analyze
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
5. Based on the following mature mRNAs, what exons are constitutive?
I. 1-2-3-4-7-8-10 II. 2-4-5-6-7-9 III. 1-4-6-7-8 IV. 1-2-4-7-10
A. 1 and 2
B. 1 and 4
C. 2 and 7
D. 4 and 7
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
6. What is an example of RNA editing?
A. Changing a valine codon to a stop codon
B. Methylation of cytosine bases
C. Formation of RISC
D. Alternative splicing
Blooms Level: 4. Analyze
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
7. Which of the following mRNAs would be found at the lowest concentration?
A. 5 GGAUGGCCGUUUGAAAAAAAAAAAAAAAAAAAAA 3
B. 5 GGAUGGCGACCUGAAUUUAAUUUAAUUUAAAAAA 3
C. 5 GGAUGGAAGUUUGAAUUUAAUUUAAAAAAAAAAA 3
D. 5 GGAUGGGGACUUGAAUUAAAAAAAAAAAAAAAAA 3
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
8. Where is the IRE located in the ferritin gene?
A. 5 end of DNA
B. 5 end of mRNA
C. 3 end of DNA
D. 3 end of mRNA
Blooms Level: 2. Understand
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
9. A mutation in which of the following would result in little or no expression of a gene regulated by a CRE?
A. G protein
B. Adenylyl cyclase
C. Protein kinase A
D. All of the answers are correct
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
10. What activates CREB?
A. Binding of cAMP
B. Phosphorylation
C. Dimerization
D. None of the answers are correct
Blooms Level: 2. Understand
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
11. What would be the result of a mutation in Hsp90?
A. Glucocorticoid receptor could not form a dimmer
B. The nuclear localization signal would no longer function
C. Expression of the regulated genes would become constitutive
D. The hormone would not be able to bind to the glucocorticoid receptor
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
12. Which mechanisms are used by miRNAs to regulate gene expression?
A. Targeted degradation of mRNAs
B. Targeted inhibition of mRNA translation
C. Both A and B
D. Neither A nor B
Blooms Level: 4. Analyze
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
13. A person with a mutation in IRP that prevents it from binding iron. What effect will this have?
A. Ferritin will not be made, so iron intake must be maximized
B. There will be excess ferritin, so iron intake must be lowered
C. Transferrin will not be made, so iron intake must be maximized
D. There will be excess transferrin, so iron intake must be lowered
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
14. What mechanism of RNA regulation is responsible for the two different forms of apolipoprotein B?
A. Alternative splicing
B. RNA editing
C. RNA interference
D. Covalent modification of RNA
Blooms Level: 3. Apply
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
15. What basal transcription factor is most often affected by regulatory transcription factors?
A. TFIIB
B. TFIID
C. TFIIE
D. TFIIF
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
16. SR proteins are splicing factors rich in _____.
A. Arginine
B. Cysteine
C. Asparagine
D. Proline
Blooms Level: 2. Understand
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
17. Which of the following relationships is true?
A. The more stable an mRNA is, the higher its concentration
B. The more unstable an mRNA is, the lower its concentration
C. The more unstable an mRNA is, the higher its concentration
D. More than one of the answers are correct
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
18. eIF2a is phosphorylated in order to inhibit transcription. What is occurring at the molecular level?
A. Phosphorylated eIF2a binds to tRNAs, preventing them from attaching its amino acid
B. Phosphorylated eIF2a binds to eIF2B, inhibiting its activity
C. Phosphorylated eIF2a binds to the mRNA, blocking the Shine-Delgarno sequence and preventing translational initiation
D. All of the answers are correct
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
19. S1 nuclease will cleave which of the following?
A. Double-stranded DNA
B. Single-stranded DNA
C. A single-stranded probe hybridized to a particular gene
D. Chromosomal DNA in an open conformation
Blooms Level: 2. Understand
Learning Outcome: 15.03: Know the relationship between chromatin structure and gene expression.
Section: 15.02
Topic: Gene Regulation
20. In which of the following scenarios would gene expression be the lowest?
A. The CpG island upstream of the gene is unmethylated
B. Injecting antisense RNA corresponding to the mRNA of the gene
C. Deletion of a sequence upstream of the gene known to be a silencer
D. Injecting double-stranded RNA corresponding to the mRNA of the gene
Blooms Level: 4. Analyze
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
21. Transcription factors recognize which of the following?
A. Response elements
B. Control elements
C. Regulatory elements
D. All of the answers are correct
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
22. Which of the following is an example of a motif found in transcription factors?
A. Zinc finger
B. Leucine zipper
C. Helix-turn-helix
D. Helix-loop-helix
E. All of the answers are correct
Blooms Level: 2. Understand
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
23. Regulatory transcription factors may influence gene expression in which of the following ways?
A. Recruiting proteins to the promoter that enhance chromatin compaction
B. By effecting the ability of TFIID to bind to the core promoter
C. Influencing the ability of the RNA polymerase to form an initiation complex
D. All of the answers are correct
Blooms Level: 5. Evaluate
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
24. Regulatory transcription factors may be regulated by __________.
A. Covalent modifications
B. Protein-protein interactions
C. Use of effector molecules
D. All of the answers are correct
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
25. Which of the following is incorrect regarding the glucocorticoid hormomes?
A. They interact with receptors located in the plasma membrane of the cell
B. After interacting with the receptor, they release HSP90
C. The receptors form a homodimer that travels to the nucleus
D. The homodimer interacts with GRE, activating transcription
Blooms Level: 4. Analyze
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones.
Section: 15.01
Topic: Gene Regulation
26. cAMP is known as a second messenger system since the pathway is first activated by a extracellular signaling molecule
TRUE
Blooms Level: 3. Apply
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones.
Section: 15.01
Topic: Gene Regulation
27. Which one of the following directly interacts with the DNA as a transcriptional regulator?
A. cAMP
B. G protein
C. Protein kinase A
D. CREB protein dimmer
E. None of the answers are correct
Blooms Level: 2. Understand
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
28. RNAi is used in eukaryotic cells only to defend against viruses and transposable elements.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
29. Histone acetyltransferases would be directly involved in which of the following?
A. Formation of open chromatin
B. Movement of the nucleosome
C. Acetylation of lysines
D. Termination of gene expression
Blooms Level: 3. Apply
Learning Outcome: 15.03: Know the relationship between chromatin structure and gene expression.
Section: 15.02
Topic: Gene Regulation
30. CpG islands are associated with which of the following?
A. Nucleosome location
B. DNA methylation
C. Steroid hormone activity
D. cAMP pathway
Blooms Level: 2. Understand
Learning Outcome: 15.04: Know the effect of DNA methylation on gene expression.
Section: 15.03
Topic: Gene Regulation
31. Genomic imprinting is a result of ___________.
A. Nucleosome location
B. Histone activation
C. DNA methylation
D. Serine to leucine changes in the genetic code
Blooms Level: 3. Apply
Learning Outcome: 15.04: Know the effect of DNA methylation on gene expression.
Section: 15.03
Topic: Gene Regulation
32. The exons of a gene are always expressed in a functional protein.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
33. Guide RNA is used in which of the following processes?
A. DNA methylation
B. Alternative splicing
C. Chromatin condensation
D. RNA editing
E. None of the answers are correct
Blooms Level: 3. Apply
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
34. The stability of mRNA is due mostly to which of the following?
A. GC content of the message
B. Poly-A binding protein
C. Methylation
D. 5 capping
E. Alternative splicing
Blooms Level: 3. Apply
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
35. Explain why yeast genes with a single intron have essentially no alternative splicing.
A. Yeast genes never have alternative splicing.
B. Removal of a single intron leads to splicing of the poly-A tail which prevents further splicing.
C. Methylation of the single intron prevents further splicing.
D. Removal of a single intron only leads to one possible outcome for spliced mRNA.
E. None of the above.
Blooms Level: 5. Evaluate
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression.
Section: 15.05
Topic: Gene Regulation
36. Transcription factors are proteins that influence the ability of the RNA polymerase to transcribe a gene.
TRUE
Blooms Level: 2. Understand
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
37. Activator proteins bind to silencer sequences and repressor proteins bind to enhancer sequences.
FALSE
Blooms Level: 4. Analyze
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
38. If a portion of a transcription factors domain is the same in a variety of organisms, it is called a motif.
TRUE
Blooms Level: 3. Apply
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
39. A heterodimer occurs when two identical transcription factors interact on a sequence of DNA.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
40. A repressor protein would enhance the ability of TFIID to bind to the TATA box of the promoter.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated.
Section: 15.01
Topic: Gene Regulation
41. Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.
TRUE
Blooms Level: 4. Analyze
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones.
Section: 15.01
Topic: Gene Regulation
42. Receptors for steroid hormones are usually found in the nucleus of the cell.
FALSE
Blooms Level: 2. Understand
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones.
Section: 15.01
Topic: Gene Regulation
43. DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.03: Know the relationship between chromatin structure and gene expression.
Section: 15.02
Topic: Gene Regulation
44. Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.
TRUE
Blooms Level: 3. Apply
Learning Outcome: 15.03: Know the relationship between chromatin structure and gene expression.
Section: 15.02
Topic: Gene Regulation
45. DNA methylation activates gene expression.
FALSE
Blooms Level: 3. Apply
Learning Outcome: 15.04: Know the effect of DNA methylation on gene expression.
Section: 15.03
Topic: Gene Regulation
46. Housekeeping genes are unmethylated and active in most cells.
TRUE
Blooms Level: 3. Apply
Learning Outcome: 15.04: Know the effect of DNA methylation on gene expression.
Section: 15.03
Topic: Gene Regulation
Chapter 15 Gene Regulation in Eukaryotes Summary
Category # of Questions
Blooms Level: 2. Understand 10
Blooms Level: 3. Apply 16
Blooms Level: 4. Analyze 12
Blooms Level: 5. Evaluate 8
Learning Outcome: 15.01: Know the types of regulatory transcription factors, their structures and DNA binding sequences, and the common ways in which they are regulated. 16
Learning Outcome: 15.02: Understand the mechanism of action of steriod hormones. 5
Learning Outcome: 15.03: Know the relationship between chromatin structure and gene expression. 4
Learning Outcome: 15.04: Know the effect of DNA methylation on gene expression. 4
Learning Outcome: 15.06: Understand how changes in RNA processing, stability, and translation can influence gene expression. 17
Section: 15.01 21
Section: 15.02 4
Section: 15.03 4
Section: 15.05 17
Topic: Gene Regulation 46
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