Introduction to Genetic Principles David R. Hyde 1st Edition Test Bank

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Introduction to Genetic Principles David R. Hyde 1st Edition Test Bank

Description

9
1. The main enzyme responsible for synthesizing DNA in bacteria is

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. DNA polymerase

E. DNA polymerase

2. The enzyme that heals nicks in DNA is

A. DNA polymerase I

B. DNA polymerase II

C. Helicase

D. Gyrase

E. Ligase

3. Which of the following acts as a template during DNA synthesis?

A. The strand that is being built

B. DNA polymerase III

C. DNA polymerase

D. DNA helicase

E. The strand that is being copied

4. After the two strands of DNA are opened, which enzyme starts DNA synthesis?

A. Helicase

B. Primase

C. Ligase

D. DNA polymerase

E. DNA polymerase III

5. The first nucleotides put in during DNA synthesis are

A. Ribonucleotides

B. Deoxyribonucleotides.

C. Ribonucleotides with thymine instead of uracil

D. Deoxyribonucleotides with uracil instead of thymine

E. Ribonucleotides with deoxyribose instead of ribose

6. Nucleotides are added to the ________ carbon atom of replicating DNA.

A. 1

B. 2

C. 3

D. 4

E. 5

7. DNA polymerases need all of the following EXCEPT

A. A primer

B. A template

C. The triphosphate form of uracil

D. The triphosphate form of thymine

E. The energy from the breakdown of a triphosphonucleotide to a monophosphonucleotide

8. DNA replication goes in the _________ direction.

A. 15

B. 23

C. 32

D. 53

E. 35

9. A piece of DNA with the sequence 5 CAATCGAT 3 is being copied. What will the new sequence be?

A. 5 GTTAGCTA 3

B. 3 GTTAGCTA 5

C. 5 CAATCGAT 3

D. 3 CAATCGAT 5

E. 3 GUUAGCUA 5

10. Semi-conservative replication means that at the end of replication the newly formed DNA will have _________, while conservative replication means that at the end of replication the newly formed DNA will have ___________.

A. Both the old strands together, one new strand with one old strand

B. Both the old strands with parallel orientation, both the new strands with anti-parallel orientation

C. One new strand with one old strand, both old strands together and both new strands together

D. A mix of old and new strands, one new strand with one old strand

E. Both the old strands together, a mix of old and new strands

11. Meselson and Stahl showed that DNA replicates

A. In a 53 direction

B. Conservatively

C. In a 35 direction

D. Semi-conservatively

E. Dispersively

12. To investigate how DNA was replicated, Meselson and Stahl used

A. 32P and ultracentrifugation

B. CsCl and radioactive thymine

C. 35S and radioactive uracil

D. 15N and ultracentrifugation

E. 15N and mice

13. In the Meselson and Stahl experiment, after two rounds of replication, the DNA distributed itself in the tube as so:

After only one round of replication, the DNA appeared as which of these?

A. A

B. B

C. C

D. D

E. E

14. What did Herb Taylor use to determine if chromosomes in eukaryotes were replicated conservatively, semi-conservatively or dispersively?

A. Tritium-labeled adenine

B. Tritium-labeled thymine

C. 15N-labeled adenine

D. 15N-labeled thymine

E. 15N-labeled uracil

15. John Cairns used autoradiography with bacteria while they were replicating their DNA and showed which of the following?

A. 1. Bacterial DNA is circular, 2. DNA is replicated without breaking the circle, 3. DNA replicates in the 53 direction

B. 1. Bacterial DNA is circular, 2. DNA replicates in the 35 direction, 3. DNA replicates from a single point of origin

C. 1. DNA is replicated without breaking the circle, 2. DNA replicates in the 53 direction, 3. DNA replicates from a single point of origin.

D. 1. Bacterial DNA is circular, 2. DNA is replicated without breaking the circle, 3. DNA replicates from a single point of origin

E. 1. DNA is replicated without breaking the circle, 2. DNA is replicated in a semi-conservative manner, 3. DNA replicates from a single point of origin

16. Bacteria have how many origins of DNA replication?

A. 0

B. 1

C. 2

D. 4

E. More than four

17. The point of origin of DNA replication was found by using autoradiography and was possible because

A. The radioactive phosphate was in the newly made DNA

B. The radioactive thymine was in the newly made DNA

C. The radioactive uracil was in the newly made DNA

D. The radioactive cytosine in the newly made DNA

E. The radioactive deoxyribose was in the newly made DNA

18. Watson and Crick elucidated the structure of DNA by

A. Building models based on known attributes of DNA

B. Performing X-ray crystallography on DNA that they isolated.

C. Labeling thymine with 15N and determining where it was in the molecule

D. Experimentally determining that the A:T ratio and the C:G ratio were approximately equal to 1 in DNA

E. Removing all of the ribose, leaving only deoxyribose in the DNA

19. DNA polymerase III adds nucleotides to the free 3 end of replicating DNA, but which enzyme adds nucleotides to the free 5 end?

A. Primase

B. DNA polymerase I

C. DNA polymerase II

D. DNA polymerase IV

E. No known enzyme can add nucleotides to a free 5 end

20. Phosphodiester bonds connect what two parts of DNA?

A. Two deoxyribose molecules

B. Adjacent bases

C. Bases on opposite strands of DNA

D. A deoxyribose to a base

E. A ribose to a deoxyribose

21. Eukaryotes have how many origins of DNA replication?

A. 0

B. 1

C. 2

D. 4

E. More than four

22. A primer for DNA synthesis is

A. A nucleic acid sequence with a free 1 end

B. A nucleic acid sequence with a free 3 end

C. A nucleic acid sequence with a free 5 end

D. Always DNA

E. Always RNA

The diagram to the left represents DNA that is actively being synthesized.

23. Which letter represents the lagging strand?

A. a

B. b

C. c

D. d

E. e

24. Which letter represents the leading strand?

A. a

B. b

C. c

D. d

E. e

25. Which letter represents the 5 end of a strand?

A. a

B. b

C. c

D. d

E. e

26. The letter e represents

A. The leading strand

B. The lagging strand

C. The template strand

D. The RNA primer

E. An Okazaki fragment

27. The letter f represents

A. The leading strand

B. The lagging strand

C. The template strand

D. The RNA primer

E. An Okazaki fragment

28. Leading strands and lagging strands exist because

A. There is no known enzyme that replicates in the 35 direction

B. Replicating DNA is composed of parallel double helices

C. There is so much primase in the cell that it must be used

D. There is not enough DNA polymerase II to copy the other strand

E. The newly made DNA uses ribose, not deoxyribose

29. Okazaki fragments are

A. Lengths of DNA on the template strand that are being copied

B. Pieces of RNA that act as a template

C. Pieces of RNA that act as a primer

D. The leading strand of DNA that has just been replicated

E. Pieces of DNA from the lagging strand before the gaps are sealed

30. Which enzyme removes the RNA primers?

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. Primase

E. Helicase

31. Which enzyme replaces the RNA primers with DNA?

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. Primase

E. Helicase

32. Which enzyme seals the gaps between Okazaki fragments?

A. DNA polymerase I

B. DNA polymerase II

C. Gyrase

D. Ligase

E. Primase

33. The protein ________ denatures the DNA at the origin of replication and the enzyme _________ then opens the double helix.

A. DnaA, DNA polymerase III

B. DnaB, gyrase

C. DnaA, helicase

D. OriC, helicase

E. Helicase, gyrase

34. oriC is

A. A protein that binds to the origin of replication

B. The origin of replication in bacteria

C. The gene that produces DNA polymerase I

D. The gene that produces primase

E. The origin of replication in eukaryotes

35. The primosome consists of

A. Helicase and gyrase

B. DnaA and helicase

C. DnaA and primase

D. Helicase and primase

E. Primase and DnaA

36. As a holoenzyme, DNA polymerase III has all of the following activities EXCEPT

A. Unwinding the DNA

B. Replicating the DNA

C. Holding the core enzymes to the template strand

D. Allowing the polymerase to leave the lagging strand template

E. A 3 exonuclease

37. The following events take place in this order:

A. Helicase and primase bind, DnaA binds, RNA primer is synthesized, the DNA is opened up

B. DnaA binds, DNA is denatured, the primosome forms, DNA is opened up, RNA primer is synthesized

C. DnaA binds, the primosome forms, RNA primer is synthesized, the DNA is opened up

D. Helicase and primase bind, DNA is opened up, DnaA binds, RNA primer is synthesized

E. Primase binds, DnaA denatures the DNA, the primosome forms, RNA primer is synthesized

38. Enzymes that can put nicks in DNA by breaking the phosophodiester bond are known as

A. Endonucleases

B. Primases

C. Helicases

D. Exonucleases

E. Gyrases

39. The proofreading activity of DNA synthesis is found in

A. 5 3 exonuclease

B. 3 5 exonuclease

C. 5 3 endonuclease

D. 3 5 endonuclease

E. Primase

40. SSB proteins serve to

A. Unwind DNA

B. Relax supercoiled DNA

C. Bind to single stranded DNA to prevent it from reannealing

D. Bind to double stranded DNA to attract the primosome

E. Act as a 5 3 exonuclease

41. As helicase is unwinding DNA it is generating what problem further down the DNA double helix?

A. It is causing double-stranded breaks

B. It is causing single-stranded breaks

C. It is causing negative supercoiling

D. It is causing positive supercoiling

E. Helicase does not cause any problems it does not unwind DNA

42. Type I topoisomerases have what activity?

A. They break one strand of DNA, pass the other strand through the break and then re-join the broken strand

B. They break two strands of DNA, pass a double helix through the break and then re-join the broken strands

C. They unwind DNA during DNA replication

D. They wind DNA so that primase can get to the DNA

E. They prevent single-stranded DNA from reannealing into double strands

43. The ter site on the E. coli chromosome serves to terminate

A. Primase activity

B. DNA polymerase I activity

C. Helicase activity

D. Gyrase activity

E. DNA polymerization

44. If two DNA molecules are catenated it means

A. They are loaded with cations

B. Their phosphates have all of their negative charges neutralized by the addition of hydrogen atoms

C. They are positively supercoiled

D. They are negatively supercoiled

E. They are interlinked

The figure to the right represents a type of DNA replication.

45. What is the name given to this type of DNA replication?

A. Circular

B. D-loop model

C. Rolling-circle model

D. Eukaryotic model

E. Mitochondrial model

46. Which letter represents the lagging strand of DNA?

A. a

B. b

C. c

D. d

E. e

47. Which letter represents the RNA primer?

A. a

B. b

C. c

D. d

E. e

48. In eukaryotes the leading strand is synthesized by DNA polymerase

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

49. In eukaryotes, DNA polymerase __________ carries the RNA primase.

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

50. DNA polymerase ____________ replicates mitochondrial DNA.

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

51. The enzyme that removes RNA primers in eukaryotes is

A. DNA polymerase

B. Gyrase

C. DNA polymerase

D. DNA polymerase

E. RNase

52. Which of the following is a repair enzyme in eukaryotes?

A. DNA polymerase (alpha)

B. DNA polymerase (beta)

C. DNA polymerase (gamma)

D. RNase

E. Ligase

53. Which of the following is a protein that is necessary for DNA replication in eukaryotes but not bacteria?

A. Kinase

B. ARS

C. OriC

D. DnaE

E. SSB

54. How can telomerase replicate the ends of chromosomes without a template on the DNA being replicated?

A. It carries its own DNA template

B. It carries its own RNA template

C. It simply connects the two ends of the chromosome

D. It forms a loop and copies the DNA in that loop

E. This statement is false-telomerase, like all other DNA polymerases must have a template on the strand that is being copied

55. Telomerase adds nucleotides to the

A. The 5 end of the DNA of the centromere

B. The 3 end of the DNA of the centromere

C. The 5 end of the DNA of the telomere

D. The 3 end of the DNA of the telomere

E. Both the 5 and 3 ends of the DNA of the telomere

9 Key

1. The main enzyme responsible for synthesizing DNA in bacteria is

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. DNA polymerase

E. DNA polymerase

Difficulty: Easy
Hyde Chapter 09 #1

2. The enzyme that heals nicks in DNA is

A. DNA polymerase I

B. DNA polymerase II

C. Helicase

D. Gyrase

E. Ligase

Difficulty: Easy
Hyde Chapter 09 #2

3. Which of the following acts as a template during DNA synthesis?

A. The strand that is being built

B. DNA polymerase III

C. DNA polymerase

D. DNA helicase

E. The strand that is being copied

Difficulty: Easy
Hyde Chapter 09 #3

4. After the two strands of DNA are opened, which enzyme starts DNA synthesis?

A. Helicase

B. Primase

C. Ligase

D. DNA polymerase

E. DNA polymerase III

Difficulty: Easy
Hyde Chapter 09 #4

5. The first nucleotides put in during DNA synthesis are

A. Ribonucleotides

B. Deoxyribonucleotides.

C. Ribonucleotides with thymine instead of uracil

D. Deoxyribonucleotides with uracil instead of thymine

E. Ribonucleotides with deoxyribose instead of ribose

Difficulty: Moderate
Hyde Chapter 09 #5

6. Nucleotides are added to the ________ carbon atom of replicating DNA.

A. 1

B. 2

C. 3

D. 4

E. 5

Difficulty: Easy
Hyde Chapter 09 #6

7. DNA polymerases need all of the following EXCEPT

A. A primer

B. A template

C. The triphosphate form of uracil

D. The triphosphate form of thymine

E. The energy from the breakdown of a triphosphonucleotide to a monophosphonucleotide

Difficulty: Moderate
Hyde Chapter 09 #7

8. DNA replication goes in the _________ direction.

A. 15

B. 23

C. 32

D. 53

E. 35

Difficulty: Moderate
Hyde Chapter 09 #8

9. A piece of DNA with the sequence 5 CAATCGAT 3 is being copied. What will the new sequence be?

A. 5 GTTAGCTA 3

B. 3 GTTAGCTA 5

C. 5 CAATCGAT 3

D. 3 CAATCGAT 5

E. 3 GUUAGCUA 5

Difficulty: Moderate
Hyde Chapter 09 #9

10. Semi-conservative replication means that at the end of replication the newly formed DNA will have _________, while conservative replication means that at the end of replication the newly formed DNA will have ___________.

A. Both the old strands together, one new strand with one old strand

B. Both the old strands with parallel orientation, both the new strands with anti-parallel orientation

C. One new strand with one old strand, both old strands together and both new strands together

D. A mix of old and new strands, one new strand with one old strand

E. Both the old strands together, a mix of old and new strands

Difficulty: Difficult
Hyde Chapter 09 #10

11. Meselson and Stahl showed that DNA replicates

A. In a 53 direction

B. Conservatively

C. In a 35 direction

D. Semi-conservatively

E. Dispersively

Difficulty: Easy
Hyde Chapter 09 #11

12. To investigate how DNA was replicated, Meselson and Stahl used

A. 32P and ultracentrifugation

B. CsCl and radioactive thymine

C. 35S and radioactive uracil

D. 15N and ultracentrifugation

E. 15N and mice

Difficulty: Difficult
Hyde Chapter 09 #12

13. In the Meselson and Stahl experiment, after two rounds of replication, the DNA distributed itself in the tube as so:

After only one round of replication, the DNA appeared as which of these?

A. A

B. B

C. C

D. D

E. E

Difficulty: Moderate
Hyde Chapter 09 #13

14. What did Herb Taylor use to determine if chromosomes in eukaryotes were replicated conservatively, semi-conservatively or dispersively?

A. Tritium-labeled adenine

B. Tritium-labeled thymine

C. 15N-labeled adenine

D. 15N-labeled thymine

E. 15N-labeled uracil

Difficulty: Moderate
Hyde Chapter 09 #14

15. John Cairns used autoradiography with bacteria while they were replicating their DNA and showed which of the following?

A. 1. Bacterial DNA is circular, 2. DNA is replicated without breaking the circle, 3. DNA replicates in the 53 direction

B. 1. Bacterial DNA is circular, 2. DNA replicates in the 35 direction, 3. DNA replicates from a single point of origin

C. 1. DNA is replicated without breaking the circle, 2. DNA replicates in the 53 direction, 3. DNA replicates from a single point of origin.

D. 1. Bacterial DNA is circular, 2. DNA is replicated without breaking the circle, 3. DNA replicates from a single point of origin

E. 1. DNA is replicated without breaking the circle, 2. DNA is replicated in a semi-conservative manner, 3. DNA replicates from a single point of origin

Difficulty: Difficult
Hyde Chapter 09 #15

16. Bacteria have how many origins of DNA replication?

A. 0

B. 1

C. 2

D. 4

E. More than four

Difficulty: Easy
Hyde Chapter 09 #16

17. The point of origin of DNA replication was found by using autoradiography and was possible because

A. The radioactive phosphate was in the newly made DNA

B. The radioactive thymine was in the newly made DNA

C. The radioactive uracil was in the newly made DNA

D. The radioactive cytosine in the newly made DNA

E. The radioactive deoxyribose was in the newly made DNA

Difficulty: Moderate
Hyde Chapter 09 #17

18. Watson and Crick elucidated the structure of DNA by

A. Building models based on known attributes of DNA

B. Performing X-ray crystallography on DNA that they isolated.

C. Labeling thymine with 15N and determining where it was in the molecule

D. Experimentally determining that the A:T ratio and the C:G ratio were approximately equal to 1 in DNA

E. Removing all of the ribose, leaving only deoxyribose in the DNA

Difficulty: Moderate
Hyde Chapter 09 #18

19. DNA polymerase III adds nucleotides to the free 3 end of replicating DNA, but which enzyme adds nucleotides to the free 5 end?

A. Primase

B. DNA polymerase I

C. DNA polymerase II

D. DNA polymerase IV

E. No known enzyme can add nucleotides to a free 5 end

Difficulty: Easy
Hyde Chapter 09 #19

20. Phosphodiester bonds connect what two parts of DNA?

A. Two deoxyribose molecules

B. Adjacent bases

C. Bases on opposite strands of DNA

D. A deoxyribose to a base

E. A ribose to a deoxyribose

Difficulty: Easy
Hyde Chapter 09 #20

21. Eukaryotes have how many origins of DNA replication?

A. 0

B. 1

C. 2

D. 4

E. More than four

Difficulty: Easy
Hyde Chapter 09 #21

22. A primer for DNA synthesis is

A. A nucleic acid sequence with a free 1 end

B. A nucleic acid sequence with a free 3 end

C. A nucleic acid sequence with a free 5 end

D. Always DNA

E. Always RNA

Difficulty: Moderate
Hyde Chapter 09 #22

The diagram to the left represents DNA that is actively being synthesized.

Hyde Chapter 09

23. Which letter represents the lagging strand?

A. a

B. b

C. c

D. d

E. e

Difficulty: Moderate
Hyde Chapter 09 #23

24. Which letter represents the leading strand?

A. a

B. b

C. c

D. d

E. e

Difficulty: Moderate
Hyde Chapter 09 #24

25. Which letter represents the 5 end of a strand?

A. a

B. b

C. c

D. d

E. e

Difficulty: Easy
Hyde Chapter 09 #25

26. The letter e represents

A. The leading strand

B. The lagging strand

C. The template strand

D. The RNA primer

E. An Okazaki fragment

Difficulty: Moderate
Hyde Chapter 09 #26

27. The letter f represents

A. The leading strand

B. The lagging strand

C. The template strand

D. The RNA primer

E. An Okazaki fragment

Difficulty: Moderate
Hyde Chapter 09 #27

28. Leading strands and lagging strands exist because

A. There is no known enzyme that replicates in the 35 direction

B. Replicating DNA is composed of parallel double helices

C. There is so much primase in the cell that it must be used

D. There is not enough DNA polymerase II to copy the other strand

E. The newly made DNA uses ribose, not deoxyribose

Difficulty: Moderate
Hyde Chapter 09 #28

29. Okazaki fragments are

A. Lengths of DNA on the template strand that are being copied

B. Pieces of RNA that act as a template

C. Pieces of RNA that act as a primer

D. The leading strand of DNA that has just been replicated

E. Pieces of DNA from the lagging strand before the gaps are sealed

Difficulty: Easy
Hyde Chapter 09 #29

30. Which enzyme removes the RNA primers?

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. Primase

E. Helicase

Difficulty: Moderate
Hyde Chapter 09 #30

31. Which enzyme replaces the RNA primers with DNA?

A. DNA polymerase I

B. DNA polymerase II

C. DNA polymerase III

D. Primase

E. Helicase

Difficulty: Easy
Hyde Chapter 09 #31

32. Which enzyme seals the gaps between Okazaki fragments?

A. DNA polymerase I

B. DNA polymerase II

C. Gyrase

D. Ligase

E. Primase

Difficulty: Easy
Hyde Chapter 09 #32

33. The protein ________ denatures the DNA at the origin of replication and the enzyme _________ then opens the double helix.

A. DnaA, DNA polymerase III

B. DnaB, gyrase

C. DnaA, helicase

D. OriC, helicase

E. Helicase, gyrase

Difficulty: Difficult
Hyde Chapter 09 #33

34. oriC is

A. A protein that binds to the origin of replication

B. The origin of replication in bacteria

C. The gene that produces DNA polymerase I

D. The gene that produces primase

E. The origin of replication in eukaryotes

Difficulty: Easy
Hyde Chapter 09 #34

35. The primosome consists of

A. Helicase and gyrase

B. DnaA and helicase

C. DnaA and primase

D. Helicase and primase

E. Primase and DnaA

Difficulty: Difficult
Hyde Chapter 09 #35

36. As a holoenzyme, DNA polymerase III has all of the following activities EXCEPT

A. Unwinding the DNA

B. Replicating the DNA

C. Holding the core enzymes to the template strand

D. Allowing the polymerase to leave the lagging strand template

E. A 3 exonuclease

Difficulty: Difficult
Hyde Chapter 09 #36

37. The following events take place in this order:

A. Helicase and primase bind, DnaA binds, RNA primer is synthesized, the DNA is opened up

B. DnaA binds, DNA is denatured, the primosome forms, DNA is opened up, RNA primer is synthesized

C. DnaA binds, the primosome forms, RNA primer is synthesized, the DNA is opened up

D. Helicase and primase bind, DNA is opened up, DnaA binds, RNA primer is synthesized

E. Primase binds, DnaA denatures the DNA, the primosome forms, RNA primer is synthesized

Difficulty: Difficult
Hyde Chapter 09 #37

38. Enzymes that can put nicks in DNA by breaking the phosophodiester bond are known as

A. Endonucleases

B. Primases

C. Helicases

D. Exonucleases

E. Gyrases

Difficulty: Easy
Hyde Chapter 09 #38

39. The proofreading activity of DNA synthesis is found in

A. 5 3 exonuclease

B. 3 5 exonuclease

C. 5 3 endonuclease

D. 3 5 endonuclease

E. Primase

Difficulty: Moderate
Hyde Chapter 09 #39

40. SSB proteins serve to

A. Unwind DNA

B. Relax supercoiled DNA

C. Bind to single stranded DNA to prevent it from reannealing

D. Bind to double stranded DNA to attract the primosome

E. Act as a 5 3 exonuclease

Difficulty: Easy
Hyde Chapter 09 #40

41. As helicase is unwinding DNA it is generating what problem further down the DNA double helix?

A. It is causing double-stranded breaks

B. It is causing single-stranded breaks

C. It is causing negative supercoiling

D. It is causing positive supercoiling

E. Helicase does not cause any problems it does not unwind DNA

Difficulty: Difficult
Hyde Chapter 09 #41

42. Type I topoisomerases have what activity?

A. They break one strand of DNA, pass the other strand through the break and then re-join the broken strand

B. They break two strands of DNA, pass a double helix through the break and then re-join the broken strands

C. They unwind DNA during DNA replication

D. They wind DNA so that primase can get to the DNA

E. They prevent single-stranded DNA from reannealing into double strands

Difficulty: Difficult
Hyde Chapter 09 #42

43. The ter site on the E. coli chromosome serves to terminate

A. Primase activity

B. DNA polymerase I activity

C. Helicase activity

D. Gyrase activity

E. DNA polymerization

Difficulty: Moderate
Hyde Chapter 09 #43

44. If two DNA molecules are catenated it means

A. They are loaded with cations

B. Their phosphates have all of their negative charges neutralized by the addition of hydrogen atoms

C. They are positively supercoiled

D. They are negatively supercoiled

E. They are interlinked

Difficulty: Difficult
Hyde Chapter 09 #44

The figure to the right represents a type of DNA replication.

Hyde Chapter 09

45. What is the name given to this type of DNA replication?

A. Circular

B. D-loop model

C. Rolling-circle model

D. Eukaryotic model

E. Mitochondrial model

Difficulty: Easy
Hyde Chapter 09 #45

46. Which letter represents the lagging strand of DNA?

A. a

B. b

C. c

D. d

E. e

Difficulty: Moderate
Hyde Chapter 09 #46

47. Which letter represents the RNA primer?

A. a

B. b

C. c

D. d

E. e

Difficulty: Easy
Hyde Chapter 09 #47

48. In eukaryotes the leading strand is synthesized by DNA polymerase

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

Difficulty: Moderate
Hyde Chapter 09 #48

49. In eukaryotes, DNA polymerase __________ carries the RNA primase.

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

Difficulty: Moderate
Hyde Chapter 09 #49

50. DNA polymerase ____________ replicates mitochondrial DNA.

A. (alpha)

B. (beta)

C. (gamma)

D. (delta)

E. (epsilon)

Difficulty: Moderate
Hyde Chapter 09 #50

51. The enzyme that removes RNA primers in eukaryotes is

A. DNA polymerase

B. Gyrase

C. DNA polymerase

D. DNA polymerase

E. RNase

Difficulty: Moderate
Hyde Chapter 09 #51

52. Which of the following is a repair enzyme in eukaryotes?

A. DNA polymerase (alpha)

B. DNA polymerase (beta)

C. DNA polymerase (gamma)

D. RNase

E. Ligase

Difficulty: Moderate
Hyde Chapter 09 #52

53. Which of the following is a protein that is necessary for DNA replication in eukaryotes but not bacteria?

A. Kinase

B. ARS

C. OriC

D. DnaE

E. SSB

Difficulty: Easy
Hyde Chapter 09 #53

54. How can telomerase replicate the ends of chromosomes without a template on the DNA being replicated?

A. It carries its own DNA template

B. It carries its own RNA template

C. It simply connects the two ends of the chromosome

D. It forms a loop and copies the DNA in that loop

E. This statement is false-telomerase, like all other DNA polymerases must have a template on the strand that is being copied

Difficulty: Easy
Hyde Chapter 09 #54

55. Telomerase adds nucleotides to the

A. The 5 end of the DNA of the centromere

B. The 3 end of the DNA of the centromere

C. The 5 end of the DNA of the telomere

D. The 3 end of the DNA of the telomere

E. Both the 5 and 3 ends of the DNA of the telomere

Difficulty: Easy
Hyde Chapter 09 #55

9 Summary

Category # of Questions
Difficulty: Difficult 10
Difficulty: Easy 22
Difficulty: Moderate 23
Hyde Chapter 09 57

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