Test Bank For Essentials of Pharmacology Health Professions 7th Edition Woodrow Colbert Smith Test Bank
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WITH ANSWERS
Essentials of Pharmacology Health Professions 7th Edition Woodrow Colbert Smith Test Bank
Drug standards require that all preparations called by the same drug name must be of uniform .
effectiveness and reliability
cost, availability, and distribution method
dosage and route of administration
strength, quality, and purity
ANSWER: d
A friend of yours is complaining about the latest drug recall, which has affected her grandmothers heart She asks you whether there are any standards to ensure that a medication is consistent with the claims of its label. How should you respond?
Sure, any reliable drug reference will do
Yes, the Controlled Substances Schedule
Possibly, but only if the physician signed a legal document
Yes, the United States Pharmacopeia and National Formulary
ANSWER: d
Which legislation requires that drug preparations containing dangerous ingredients have a labeled container indicating the ingredient?
Pure Food and Drug Act
Controlled Substances Act
Drug Adulteration Prevention Act
Federal Food, Drug, and Cosmetic Act
ANSWER: a
What was the first law in the United States to require all drugs marketed in the United States to meet minimal standards of strength, purity, and quality?
Federal Food, Drug, and Cosmetic Act
Pure Food and Drug Act
Controlled Substances Act
Drug Adulteration Prevention Act
ANSWER: b
What are legend drugs?
Drugs that are exceptionally safe and effective
Drugs that have the phrase Cautionfederal law prohibits dispensing without a prescription on the label
Drugs that are manufactured before the Pure Food and Drug Act and therefore exempt from regulation
Drugs that have limited profitability because they are used to treat rare illnesses
ANSWER: b
Quinn hears on the news that the FDA has asked a company to withdraw a Under what circumstances can the FDA do this?
when more effective alternatives are available
never, because only the DEA can do this
when it is no longer profitable
when the benefits of a drug outweigh its risks
ANSWER: d
What legislation was created in response to a 1937 incident in which an inadequately tested drug caused the deaths of 100 people?
Drug Adulteration Prevention Act
Pure Food and Drug Act
Controlled Substances Act
Federal Food, Drug, and Cosmetic Act
ANSWER: d
What legislation requires that new drugs be approved before they are released to the public?
The Drug Adulteration Prevention Act
The Federal Food, Drug, and Cosmetic Act
The Pure Food and Drug Act
The Controlled Substances Act
ANSWER: b
Your friend, Thomas, had a serious adverse reaction to an over-the-counter medication and found that a number of other individuals had similar adverse Which agency is most likely to investigate this situation and take action if a problem is found?
Food and Drug Administration
United States Pharmacopeia
National Formulary Enforcement
Drug Enforcement Agency
ANSWER: a
What agency was established by the Federal Food, Drug, and Cosmetic Act?
The Schedule of Controlled Substances Oversight Committee
The United States Pharmacopeia and National Formulary
The Drug Enforcement Administration
The Food and Drug Administration
ANSWER: d
What agency would you expect to inspect plants where food, drugs, medical devices, and cosmetics are made?
The Drug Enforcement Agency
The Food and Drug Administration
The National Formulary
The Inspector General
ANSWER: b
In what context are you most likely to see references to USP/NF?
Characterization of addiction and abuse potential
Identification of indications and contraindications
Discussion of drug standards
Warning labels
ANSWER: c
What agency was established as a result of the Controlled Substances Act?
The Drug Enforcement Administration
The National Institute on Drug Abuse
The Food and Drug Administration
The United States Pharmacopeia
ANSWER: a
After losing your cousin to an overdose of cocaine, you decide to get involved in law enforcement activities related to illicit Which agency is most likely to interest you?
Food and Drug Administration
Drug Enforcement Administration
Substance Abuse and Mental Health Services Administration
National Institute on Drug Abuse
ANSWER: b
Ian, a registered nurse, maintains that he is not a drug abuser, so the 1970 Controlled Substances Act has no relevance for Is he right?
Yes, except that his state licensing board may place additional restrictions on
Yes, as long as he does not abuse drugs, this act does not impact
No, as long as he is careful to avoid the appearance of impropriety and is generally responsible in his all aspects of
No, because the act lays out his responsibilities with respect to record keeping and administration of controlled
ANSWER: d
Youre waiting in line at the pharmacy to get your medication, and decide to take a look at your doctors handwriting on the You notice the phrase DEA Number followed by a code. What does the phrase DEA Number represent?
The code required to determine whether the drug is reimbursable
The physicians license number for your state
The drug standards met by the medication prescribed for you
The registration number for physicians who prescribe controlled substances
ANSWER: d
Under the schedules used in the United States, which drugs have high abuse potential and can be dispensed only with a written prescription?
5 (C-V)
2 (C-II)
1 (C-I)
3 (C-III)
ANSWER: b
Drugs on which schedule may have prescriptions written out by a health care practitioner, but must be signed by the physician?
2 (C-II)
3 (C-III)
1 (C-I)
4 (C-IV)
ANSWER: d
Which schedule includes cough suppressants containing codeine and medications for diarrhea?
3 (C-III)
1 (C-I)
5 (C-V)
4 (C-IV)
ANSWER: c
To which schedule do mescaline and ecstasy belong?
4 (C-IV)
1 (C-I)
3 (C-III)
2 (C-II)
ANSWER: b
According to your text, who is an excellent resource for you when you are unsure of your legal responsibilities with drugs or have uncertainties about drug therapy?
a local pharmacist
a DEA agent
a pharmaceutical sales representative
an attorney
ANSWER: a
Your friend is working at a group home for people with severe developmental disabilities and tells you he administers You know he is not a doctor or nurse and is not, in fact, any sort of licensed health professional. Is this legal?
Possibly, as long as a registered nurse is standing right beside him when he administers
Probably, but only the physician is aware of whats happening, and if the information is kept
Yes, because unlicensed assistive personnel can legally administer
Absolutely not, because the facility can lose its license and certification for allowing
ANSWER: c
Jesse often complains about government regulation and maintains that only drugs with potential for abuse or addiction should require What other medications require prescriptions in the United States?
Those that have the potential for serious adverse effects if taken improperly
Those that are covered by insurance or other reimbursement sources
Those that are still protected by patents
None; only controlled substances need prescriptions in the S.
ANSWER: a
After being hospitalized for heart failure, 72-year-old Donna returns home with prescription With a renewed focus on her health, she also decides to start taking herbal supplements. Can this create problems?
Possibly, but only if she is also taking incorrect doses of the prescription
Possibly, but only if she takes higher doses of the herbal supplements than recommended on the
No, because manufacturers must prove that herbal supplements are safe before marketing
Yes, because herbal supplements can interact with many medications she should consult her physician
ANSWER: d
What is the term for drugs used to treat rare diseases that, because they will be used for so few people, have low profitability?
low margin drugs
compassionate use drugs
generic drugs
orphan drugs
ANSWER: d
Finlay has metastatic colon cancer and is taking an agent that stops the tumors from being able to form blood This type of drug is called a(n).
antiangiogenesis drug
biologically active drug
tacrine-type drug
anxiolytic
ANSWER: a
In the 1990s, an investigational new drug was developed to slow the progression of Alzheimers, but it was subsequently removed from the market due to liver What was this drug?
Cognex
Retrovir
Caduet
Roferon
ANSWER: a
A research team recently identified a gene associated with epidermolysis bullosa, a disease that causes skin to blister and tear with even slight friction, by searching through a massive database of genetic information using powerful This use of computers is an example of .
disease DNA
genetic mining
bioanalysis
chemoinformatics
ANSWER: d
Oriannas insulin was made using the DNA of two different What is this technique called?
gene therapy
cloning
recombinant DNA
pharmacogenetics
ANSWER: c
After identifying a gene that causes the skin of patients with epidermolysis bullosa (EB) to be easily blistered and torn, researchers have found a method to make the gene produce collagen needed for healthy skin, at least in the Researchers hope to be able to use the same process in real life, and enable patients with EB to have healthy skin. Fixing malfunctioning genes is an example of .
transgenics
gene therapy
mutagenics
translocation
ANSWER: b
Your cousin is started on medication after being diagnosed with Because he experiences seizures quite often, he starts with a very large dose of the anticonvulsant to elevate the levels of the drug in his blood as quickly as possible. This initial, large dose is known as a(n) .
overdose
loading dose
shock dose
therapeutic dose
ANSWER: b
The cellular changes produced by drugs are known as drug .
interactions
actions
effects
impacts
ANSWER: b
The physiologic changes produced by drugs are known as drug.
actions
effects
interactions
impacts
ANSWER: b
After experiencing several dangerous blood clots, Blair is prescribed an She initially takes high doses to get her blood levels of the anticoagulant up as quickly as possible, and then is placed on a lower dose for the foreseeable future. This latter, lower dose is referred to as a.
routine dose
standard dose
maintenance dose
loading dose
ANSWER: c
Your friend has recently had a baby, and visits her doctor because of a terribly sinus The doctor wants to know whether she is breastfeeding her baby. What drug process is of concern?
absorption
distribution
metabolism
excretion
ANSWER: b
The process of a drug being broken down and altered to more water-soluble by-products is known as.
biotransformation
degradation
disassembly
solubility
ANSWER: a
Why are persons with liver failure particularly prone to experiencing the toxic effects of medications?
They do not excrete the medication
They distribute the medication
They are unable to properly metabolize the
They absorb the medication too
ANSWER: c
Drug information for prescribing a certain medication indicates that it should be used with extreme caution in patients with impaired kidney What drug process is likely of concern?
absorption
metabolism
excretion
distribution
ANSWER: c
Ozzies doctor tells him not to take his tetracycline with dairy products because the calcium in the dairy products will form an insoluble complex with the What is this process called?
chelation
adsorption
oxidation
excretion
ANSWER: a
The instructions for your medication state to Take on an empty What drug process will taking the medication on an empty stomach most likely affect?
absorption
distribution
metabolism
excretion
ANSWER: a
Briella is given probenecid along with penicillin in order to build up the level of penicillin by decreasing its The effect of the probenecid is called.
synergism
potentiation
antagonism
agonism
ANSWER: b
Zach normally takes an antianxiety medication and, after he has his wisdom teeth pulled, takes a narcotic pain medication as He suddenly finds himself very drowsy and disoriented. This is an example of.
undesirable antagonism
desirable synergism
desirable antagonism
undesirable synergism
ANSWER: d
Will visits the emergency room because of a badly broken He is given a narcotic pain killer, but quickly becomes extremely dizzy and disoriented, and vomits. Will is then given another medication, naloxone, and soon begins to feel better. The effect of naloxone on the narcotic pain killer is known as.
undesirable antagonism
desirable antagonism
desirable potentiation
undesirable potentiation
ANSWER: b
Drugs with an alkaline pH are best absorbed in the.
large intestine
mouth
stomach
small intestine
ANSWER: d
You are reading about the treatment of cardiovascular disease and learn that some medications are more effective in African Americans than persons of other The study of why medications vary in effectiveness among groups is known as.
genetic therapy
epigenetics
behavioral genetics
pharmacogenomics
ANSWER: d
Your uncle takes nitroglycerin, a vasodilator, for angina, a type of chest When he feels pain from angina, he places a nitroglycerin tablet under his tongue and lets it dissolve. This route of administration is known as.
subcutaneous
sublingual
buccal
transdermal
ANSWER: b
What route of administration is the easiest, but is often slower than other routes?
subcutaneous
oral
IM
IV
ANSWER: b
Your healthy and active grandfather strains his back while helping you move your You have injured your back as well, so you give him the same over-the-counter pain reliever as the one you take, and in the same dosage. Unfortunately, your grandfather quickly develops severe stomach pain and is found to be bleeding into his stomach. What has he experienced?
contraindication
adverse reaction
abnormal reaction
secondary interaction
ANSWER: b
Your friend is given an antianxiety medication before a medical Rather than relaxing, however, your friend becomes agitated and starts shouting at people. This type of reaction is known as a(n).
reversal
anaphylactic reaction
antagonistic reaction
paradoxical reaction
ANSWER: d
The decreased response to a drug that develops after repeated doses are given is known as.
physical dependence
dose-response paradox
withdrawal
tolerance
ANSWER: d
The fat soluble vitamins are.
A, C, E
C, D, K, and folate
the B vitamins
A, D, E, and K
ANSWER: d
Megan has been taking 65,000 units of vitamin A per What is she risking with this dosage?
night blindness
joint and muscle pain
impaired immunity
delayed wound healing
ANSWER: b
In adults, neuritis, dermatitis, nausea, vomiting, and depression are associated with.
B2deficiency
B12deficiency
B1deficiency
B6deficiency
ANSWER: d
Your patient presents with night blindness, anorexia, weight loss, dry skin and eyes, and What should you suspect?
vitamin E overdose
vitamin A deficiency
folate deficiency
excess B12
ANSWER: b
Patients who are vitamin K deficient or on oral anticoagulants may experience bleeding if they overdose on vitamin
____.
E
C
D
A
ANSWER: a
Irving takes an What vitamin may cause bleeding if he takes more than 1,200 units?
D
A
E
K
ANSWER: c
Freezing food results in substantial loss of.
B1
B6
B2
B12
ANSWER: b
Pernicious anemia is associated with deficiency of vitamin .
B2
B6
B1
B12
ANSWER: d
Folic acid can interfere with the action of.
thiazide diuretics
colchicine
digoxin
phenytoin
ANSWER: d
The vitamin that is responsible for regulating the absorption and metabolism of calcium and phosphorus for healthy bones and teeth is vitamin.
E
A
C
D
ANSWER: d
Illyich is a 58-year-old chronic alcoholic who is seen at the clinic with glossitis, cheilosis, dermatitis, and photophobia. What is a possible diagnosis?
thiamine deficiency
cobalamin overdose
pyridoxine overdose
riboflavin deficiency
ANSWER: d
Alba has heard that vitamin D deficiency is common and has begun taking high dose What is a sign of vitamin D overdose?
osteomalacia
tetany
heart rhythm abnormalities
osteoporosis
ANSWER: c
Alva complains of severe muscle cramps and testing reveals that, at age 27, she also has What should you suspect?
vitamin K overdose
vitamin E overdose
vitamin D deficiency
vitamin C deficiency
ANSWER: c
Headache, flushing, and burning sensations of face, neck, and chest and postural hypotension are associated with high doses of.
thiamine
riboflavin
niacin
folate
ANSWER: c
What vitamin is unstable when exposed to heat or air or combined with alkaline compounds?
vitamin E
vitamin A
vitamin D
vitamin C
ANSWER: d
The vitamin necessary for formation of intracellular substances such as collagen is vitamin.
A
D
C
E
ANSWER: c
Thiamine is also called vitamin.
B12
B2
B6
B1
ANSWER: d
Vitamin B12 is also called.
riboflavin
cobalimin
thiamine
pyridoxine
ANSWER: b
Rickets in children is associated with.
zinc overdose
potassium deficiency
calcium deficiency
iron overdose
ANSWER: c
What is the percentage of sodium chloride in normal saline? 0.45%
1.8%
0.22%
0.9%
ANSWER: d
Fall in the blood pressure and cardiac arrhythmias are associated with .
zinc deficiency
potassium overdose
calcium deficiency
sodium overdose
ANSWER: b
The chemical symbol for iron is.
Fe
In
Pb
I
ANSWER: a
Postmenopausal women may benefit from supplemental.
folate
potassium
vitamin E
calcium
ANSWER: d
Any compound that fights against the destructive effects of free radicals is called a(n).
antiradical
antioxidant
radical antagonist
oxidation inhibitor
ANSWER: b
According to DSHEA, under what circumstances can the FDA place restrictions on a dietary supplement that is already on the market?
The FDA must show that the product is unsafe before it can order
If the FDA determines that the manufacturer did not perform sufficient safety and efficacy testing, it can order
The FDA must demonstrate that the product is neither safe nor effective in treating the diseases for which it is marketed to be able to order
If the FDA receives complaints of serious adverse effects in more than 1% of users of the supplement, it can order
ANSWER: a
The fat soluble vitamins are.
A, C, E
C, D, K, and folate
the B vitamins
A, D, E, and K
ANSWER: d
Megan has been taking 65,000 units of vitamin A per What is she risking with this dosage?
night blindness
joint and muscle pain
impaired immunity
delayed wound healing
ANSWER: b
In adults, neuritis, dermatitis, nausea, vomiting, and depression are associated with.
B2deficiency
B12deficiency
B1deficiency
B6deficiency
ANSWER: d
Your patient presents with night blindness, anorexia, weight loss, dry skin and eyes, and What should you suspect?
vitamin E overdose
vitamin A deficiency
folate deficiency
excess B12
ANSWER: b
Patients who are vitamin K deficient or on oral anticoagulants may experience bleeding if they overdose on vitamin
____.
E
C
D
A
ANSWER: a
Irving takes an What vitamin may cause bleeding if he takes more than 1,200 units?
D
A
E
K
ANSWER: c
Freezing food results in substantial loss of.
B1
B6
B2
B12
ANSWER: b
Pernicious anemia is associated with deficiency of vitamin .
B2
B6
B1
B12
ANSWER: d
Folic acid can interfere with the action of.
thiazide diuretics
colchicine
digoxin
phenytoin
ANSWER: d
The vitamin that is responsible for regulating the absorption and metabolism of calcium and phosphorus for healthy bones and teeth is vitamin.
E
A
C
D
ANSWER: d
Illyich is a 58-year-old chronic alcoholic who is seen at the clinic with glossitis, cheilosis, dermatitis, and photophobia. What is a possible diagnosis?
thiamine deficiency
cobalamin overdose
pyridoxine overdose
riboflavin deficiency
ANSWER: d
Alba has heard that vitamin D deficiency is common and has begun taking high dose What is a sign of vitamin D overdose?
osteomalacia
tetany
heart rhythm abnormalities
osteoporosis
ANSWER: c
Alva complains of severe muscle cramps and testing reveals that, at age 27, she also has What should you suspect?
vitamin K overdose
vitamin E overdose
vitamin D deficiency
vitamin C deficiency
ANSWER: c
Headache, flushing, and burning sensations of face, neck, and chest and postural hypotension are associated with high doses of.
thiamine
riboflavin
niacin
folate
ANSWER: c
What vitamin is unstable when exposed to heat or air or combined with alkaline compounds?
vitamin E
vitamin A
vitamin D
vitamin C
ANSWER: d
The vitamin necessary for formation of intracellular substances such as collagen is vitamin.
A
D
C
E
ANSWER: c
Thiamine is also called vitamin.
B12
B2
B6
B1
ANSWER: d
Vitamin B12 is also called.
riboflavin
cobalimin
thiamine
pyridoxine
ANSWER: b
Rickets in children is associated with.
zinc overdose
potassium deficiency
calcium deficiency
iron overdose
ANSWER: c
What is the percentage of sodium chloride in normal saline? 0.45%
1.8%
0.22%
0.9%
ANSWER: d
Fall in the blood pressure and cardiac arrhythmias are associated with .
zinc deficiency
potassium overdose
calcium deficiency
sodium overdose
ANSWER: b
The chemical symbol for iron is.
Fe
In
Pb
I
ANSWER: a
Postmenopausal women may benefit from supplemental.
folate
potassium
vitamin E
calcium
ANSWER: d
Any compound that fights against the destructive effects of free radicals is called a(n).
antiradical
antioxidant
radical antagonist
oxidation inhibitor
ANSWER: b
According to DSHEA, under what circumstances can the FDA place restrictions on a dietary supplement that is already on the market?
The FDA must show that the product is unsafe before it can order
If the FDA determines that the manufacturer did not perform sufficient safety and efficacy testing, it can order
The FDA must demonstrate that the product is neither safe nor effective in treating the diseases for which it is marketed to be able to order
If the FDA receives complaints of serious adverse effects in more than 1% of users of the supplement, it can order